To whom do I report email ads' I receive that will not let me unsuscribe from them? I want to stop their email?

I get various company advertising in my email in box, mostly from one company called "Generous Genie". It is a Daily ritual for me to go through my email each morning and delete ads from the same company again and again. When I try to unsubscribe, the message, "request is not valid", appears on screen. How can I unsubscribe to "Generous Gennie" nuisance?